Injections or IV’s are often recommended to female patients who are trying to conceive naturally and for those preparing for an IUI or IVF cycle. Aged oocytes have significantly reduced amounts of mitochondria (the cells that produce ATP, a source of energy) due to both time and oxidative stress, leading to suboptimal oocyte maturation, decreased fertilization rates and poor embryo development. The goal of injection therapy is to support the reduction of oxidative stress and optimize mitochondria function, thereby improving fertility rates and increasing the chances of creating a healthy baby.

The nutrients that are required for healthy mitochondrial function that could be added to injections or IVs include;

• Magnesium
• B vitamins such as B12 (methylcobalamin), active folate (MTHF) and B complex (b1, 2, 3, 5, 6)
• Nicotinamide riboside
• N-Acetyl-Cysteine
• L-carnitine
• Glutathione
• Methionine
• Inositol
• Choline
• Taurine

Vitamin C is also beneficial when added to an IV as it can increase progesterone levels (the hormone that helps prepare the uterus for pregnancy).

L-Arginine can be added to improve the uterine lining.

GSH Shots

Glutathione administration can be a stand-alone IV or injection (10 min appointments) that can be added to the end of an IV drip or acupuncture appointment.

Glutathione is our most powerful antioxidant and has the ability to prevent cellular damage caused by oxidative stress (free radicals ROS). Oxidative stress is caused by the consumption of poor quality vegetable oils and sugar, chronic emotional stress, environmental toxins, poor sleep, lack of exercise, infections, and deficiencies in antioxidant intake.

GSH & Fertility

Oxidative stress can negatively impact the reproductive cells of both males and females. There is a link between glutathione deficiency and defective sperm motility in patients with male factor infertility. For females, glutathione protects eggs from oxidative stress damage during folliculogenesis, thereby improving egg quality. Studies have shown that oocytes with higher glutathione levels produce healthier and stronger embryos. It has also been shown that for women going through IVF, follicles with higher glutathione levels ended up with higher fertilization rates. For full information on the effects of glutathione on fertility read this article.

IV drips or Injections are recommended for male patients as these nutrients are important for healthy sperm – L-Carnitine (can improve sperm motility), folate (deficiencies contribute to lower testosterone levels and male factor infertility), B12, B complex, minerals (zinc, selenium, chromium), antioxidants and Vitamin C, as well as taurine (stress reduction),  could be part of your recommended formulation.

Note: Vitamin C is extremely important for men with poor endothelial (blood vessel) health, cardiovascular issues, and high cholesterol.

GSH Shots

Glutathione administration can be a stand-alone IV or injection (10 min appointments) that can be added to the end of an IV drip or acupuncture appointment.

Glutathione is our most powerful antioxidant and has the ability to prevent cellular damage caused by oxidative stress (free radicals ROS). Oxidative stress is caused by the consumption of poor quality vegetable oils and sugar, chronic emotional stress, environmental toxins, poor sleep, lack of exercise, infections, and deficiencies in antioxidant intake. Oxidative stress can negatively impact the reproductive cells of both males and females. There is a link between glutathione deficiency and defective sperm motility in patients with male factor infertility. 

Even when fertilization is achieved, oxidative stress-induced damage and poor blood circulation may cause poor uterine lining function and luteal phase hormonal production resulting in implantation failure, poor embryo development, and miscarriage.

Glutathione, and other antioxidants, as well as certain amino acids, B vitamins (B complex, folate, B12), and other nutrients (methionine, choline) that can reduce the impact of oxidative stress (cell mitochondria / DNA damage), aid in reducing homocysteine levels (improving blood flow to reproductive organs), support normal DNA methylation, and regulate inflammation (possibly helping mitigate autoimmune factors). 

Read this article to learn more about glutathione and fertility.

IV’s or Injections are given in the weeks/months before conception (depending on need) and may continue during pregnancy.

Hormone balance and insulin regulation are key treatment principles with regards to PCOS. This is accomplished through stress reduction, proper diet and weight loss, exercise, and proper nutritional supplementation.  Commitment and time most often produces the desired results of ovulation and increased fertility, reduced weight, and less hair growth and acne (male hormones). 

Injections or IV’s are an effective way to deliver important nutrients recommended such as; inositol, methionine, choline, B complex, folate,  B12, and amino acids.

• METHIONINE
  • This is an essential amino acid (not produced by the body) that produces SAMe (alleviates stress & depression), enhances liver detoxification, decreases homocysteine levels, improves skin hair and nail health, reduces abnormal fat deposits (when injected), and produces creatine for cardiovascular and muscular health.
• INOSITOL
  • This vitamin-like substance is best known for its effects on insulin sensitivity and blood sugar (PCOS, diabetes). It’s anxiolytic and serotonin activity modulation functions help reduce anxiety and depression. It optimizes the body’s ability to break down fat (more effective when injected) and cholesterol and also helps promote hair growth.
• CHOLINE
  • Uses homocysteine to produce methionine (see above), SAMe (depression), and folate (see below). Enhances memory (nootropic). Controls cholesterol and high blood pressure. *Choline is found primarily in animal foods.
• B COMPLEX
  • B1 (thiamine) plays an essential role in metabolism by helping convert nutrients (carbohydrates, amino acids, & fatty acids) into energy.
  • B2 (riboflavin) helps convert food into energy, is an antioxidant, and helps metabolize folate.
  • B3 (niacin) plays a role in cellular signaling, metabolism and DNA production and repair. Also a precursor to NAD which slows aging (mitochondria).
  • B5 (pantothenic acid) helps your body obtain energy from food and is also involved in hormone and cholesterol production. 
  • B6 (pyridoxine) is involved in amino acid metabolism, red blood cell production, the creation of neurotransmitters, and the reduction of homocysteine.
• FOLATE (B9)
  • Needed for cell growth, amino acid metabolism, the formation of red and white blood cells, and proper cell division.
• B12 (cobalamin)
  • Vital for neurological (brain) function, DNA production, and red blood cell development. *B12 is found primarily in animal foods.
• TAURINE
  • Non-essential amino acid (*found primarily in animal foods) that supports normal blood-sugar metabolism and adipose tissue (fat) production (weight management). Is an antioxidant and anxiolytic (nervous system depressant / anti-anxiety). Necessary for the growth of muscle, eyes, and nervous system tissue. Supports cardiovascular health (regulates LD cholesterol production).
• CARNITINE
  • This amino acid is found primarily in animal foods. It improves the utilization of fat for energy (in the mitochondria) and improves insulin resistance (by reducing fat storage). It has displayed anti-aging properties (slows the decline of mitochondria health). Research demonstrates positive effects on sperm count and motility. Also may improve athletic performance and cardiovascular health.

In Polycystic Ovary Syndrome (PCOS) oxidative stress (inflammation) has been shown to be involved in mediating insulin resistance and androgen hormone increases. Glutathione injection treatment strategies to boost exhausted antioxidant levels so the body can reduce oxidative stress and inflammation are very important. Read more about this important option here.

MIC+ Injections

These are recommended to any patient that is in need of stress reduction, increased energy, weight loss, improved digestion, and detoxification (heavy metals, homocysteine).

The nutrients included in a typical MIC+ injection are as follows;

• METHIONINE
  • This is an essential amino acid (not produced by the body) that produces SAMe (alleviates stress & depression), enhances liver detoxification, decreases homocysteine levels, improves skin hair and nail health, reduces abnormal fat deposits (when injected), and produces creatine for cardiovascular and muscular health. Finally, methionine can be utilized for glutathione production.
• INOSITOL
  • This vitamin-like substance is best known for its effects on insulin sensitivity and blood sugar (PCOS, diabetes). It’s anxiolytic and serotonin activity modulation functions help reduce anxiety and depression. It optimizes the body’s ability to break down fat (more effective when injected) and cholesterol and also helps promote hair growth.
• CHOLINE
  • Uses homocysteine to produce methionine (see above), SAMe (depression), and folate (see below). Enhances memory (nootropic). Controls cholesterol and high blood pressure. *Choline is found primarily in animal foods.
• B COMPLEX
  • B1 (thiamine) plays an essential role in metabolism by helping convert nutrients (carbohydrates, amino acids, & fatty acids) into energy.
  • B2 (riboflavin) helps convert food into energy, is an antioxidant, and helps metabolize folate.
  • B3 (niacin) plays a role in cellular signaling, metabolism and DNA production and repair. Also a precursor to NAD which slows aging (mitochondria).
  • B5 (pantothenic acid) helps your body obtain energy from food and is also involved in hormone and cholesterol production. 
  • B6 (pyridoxine) is involved in amino acid metabolism, red blood cell production, the creation of neurotransmitters, and the reduction of homocysteine.
• FOLATE (B9)
  • Needed for cell growth, amino acid metabolism, the formation of red and white blood cells, and proper cell division.
• B12 (cobalamin)
  • Vital for neurological (brain) function, DNA production, and red blood cell development. *B12 is found primarily in animal foods.
• TAURINE
  • Non-essential amino acid (*found primarily in animal foods) that supports normal blood-sugar metabolism and adipose tissue (fat) production (weight management). Is an antioxidant and anxiolytic (nervous system depressant / anti-anxiety). Necessary for the growth of muscle, eyes, and nervous system tissue. Supports cardiovascular health (regulates LD cholesterol production).
• CARNITINE
  • This amino acid is found primarily in animal foods. It improves the utilization of fat for energy (in the mitochondria) and improves insulin resistance (by reducing fat storage). It has displayed anti-aging properties (slows the decline of mitochondria health). Research demonstrates positive effects on sperm count and motility. Also may improve athletic performance and cardiovascular health.
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